9838-23 Enzymology 2

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Description: Learn how and when specific enzymes are measured and improve your ability to relate enzyme levels to disease. Continue your studies from Enzymology 1 as you consider enzymes of clinical importance. You will consider detailed enzyme profiles, their tissues of origin and factors that affect their specific activity.
Start date: Upon registration
Completion: Up to 52 weeks

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FREE FOR MEMBERS!

Description: Learn how and when specific enzymes are measured and improve your ability to relate enzyme levels to disease. Continue your studies from Enzymology 1 as you consider enzymes of clinical importance. You will consider detailed enzyme profiles, their tissues of origin and factors that affect their specific activity.

Start date: Upon registration

Completion: Up to 52 weeks

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Learning Outcomes:

Define the terms plasma specific enzymes, non-plasma specific enzymes, enzymes of secretion, enzymes of cellular metabolism
Name the enzymes of importance in the diagnosis of alcoholic cirrhosis, bone disease, hepatobiliary disease, hepatocellular disease, muscle conditions, and pancreatic disease.
Define the specimen collection and storage conditions for commonly tested enzymes.
State the effect of hemolysis, storage temperature and storage pH (where applicable) on measured enzyme activity.
For each of the enzymes commonly tested in the lab state/define/explain, as appropriate: the IUB name, EC number, classification, optimum pH, origin, mechanism of action, substrates, inhibitors, cofactors, assay principle, the compound measured in the final step, necessary precautions, reference range and clinical significance.

Course Revisions: Eleanor Hooley BSc MLS, MLT

Original Author: John Chapman, FCSMLS, FIMLS, CLSp(H)

Version Date: May 2023

PEP hours: 12

CPS credits: 0

*Note: PEP hours and/or CPS credits will only be awarded upon successful completion of Final Exam.

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