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Description: Explore monocytes and macrophages and their role in the functioning of the body’s innate primary defence mechanism.

Start Date: Upon registration

Completion: Up to 52 weeks

Learning Outcomes:

• Describe the morphological appearance of monocyte.
• List the general functions of monocytes and macrophages.
• Outline the development of monocytes and macrophages.
• List the common surface markers of the developing monocyte series.
• Describe the hematopoietic growth factors that influence monocyte development.
• Tabulate the locations and names of the specific tissue macrophages.
• List the specific names of tissue macrophages and where they are located.
• Describe the unique functions of tissue macrophages where they are important.
• Describe the role of monocytes as part of innate immunity.
• Describe the functions of macrophages as phagocyte cells.
• Outline the role of phagocytes as accessory cells.
• List the important products that macrophages secrete.
• Describe the function of macrophages in wound healing and as an anti-tumor agent.
• Describe how macrophages are involved in various infectious and malignant disease processes.

Author: John Chapman, FCSMLS, FIMLS, CLSp(H)

Version Date: October 2018

PEP hours: 15.8

CPS credits: 0.64

*Note: PEP hours and/or CPS credits will only be awarded upon successful completion of Final Exam.