9817-18 Introduction to Platelet Structure and Function
Credits awarded per Session. See individual Sessions for further details.
Credits awarded
Sub type
Certificate awarded

About this item

Course includes study material and exam. 

Description: Learn about platelet production, kinetics and regulation, aggregation and understand the effect of drugs on platelets. Platelet factors and the arachidonic acid-prostacyclin pathways are also discussed.


Course/Activity Information

Learning Outcomes:

  • Describe the production of platelets in the body including platelet regulation, kinetics, and lifespan.
  • Describe in detail the ultrastructure of a typical platelet.
  • Draw a platelet showing its ultrastructure.
  • Outline the relationships between the different structural zones of the platelet.
  • Describe the current understanding of the regulatory protein thrombopoietin.
  • Briefly describe the formation of a platelet hemostatic plug.
  • Give a detailed review of the platelet interaction with the vessel wall.
  • Describe the process of aggregation and list the agents that initiate it in vitro.
  • List many of the substances available over the counter that contains aspirin.
  • Outline the logic for daily aspirin therapy.
  • Outline some of the agents that inhibit platelet aggregation.
  • Prepare a list of drugs that have an effect on platelet function
  • Outline the specific features of PF3 and PF4.
  • Describe schematically the arachidonic acid - prostacyclin pathways.
  • List the important compounds released from platelets upon activation.
  • Describe the effect of ethanol consumption on platelets.


Author: John Chapman, FCSMLS, FIMLS, CLSp(H)

Version Date: March 2018


PEP hours: 13.2

CPS credits: 0.8

*Note: PEP hours and/or CPS credits will only be awarded upon successful completion of Final Exam.

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