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Philip Britz-McKibbin - New Advances in Comprehensive Drug Surveillance in An Era of Polypharmacy, Anxiety and Pandemic  Virtual Event 24/06/2021 12pm (ET)
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Description: New technologies are urgently needed for broad spectrum drug screening given an alarming increase in drug overdose fatalities exacerbated during a pandemic. Immunoassays are widely used for urine drug testing, but are prone to bias due to antibody cross-reactivity. We will discuss a high throughput platform for nontargeted screening of a broad array of drugs of abuse in urine based on multisegment injection-capillary electrophoresis-mass spectrometry. This platform offers a rapid yet accurate platform for comprehensive surveillance of prescribed and illicit drugs of abuse among high-risk clinically depressed patients, as well as recent tobacco smoke exposures in large populations globally.

Date: June 24, 2021

Time: 12pm - 1pm (ET)

Course/Activity Information

At the end of this session you will be able to:

  • Learn about an alarming worldwide public health crisis related to prescription drug abuse as related to pain management and mental health that have been exacerbated during a pandemic.
  • Appreciate limitations of conventional targeted drug screening methods applied to human urine based on immunoassays in clinical medicine, as well as self-reporting via questionnaires frequently used in epidemiology.
  • Understand the benefits of multiplexed separation techniques when coupled to high resolution mass spectrometry for high throughput screening of a wide range of drugs of abuse and their metabolites in urine, including tobacco smoke exposure.

Speaker: Philip Britz-McKibbin (PhD)

Professor, Department of Chemistry and Chemical Biology

McMaster University, Hamilton, ON, Canada

Philip Britz-McKibbin is a Professor in the Department of Chemistry and Chemical Biology at McMaster University in Hamilton, Canada. He is currently a Cystic Fibrosis Canada Researcher. Dr. Britz-McKibbin obtained his BSc in Chemistry (U. Toronto, 1994), and PhD in Analytical Chemistry (UBC, 2000) and a Japan Society for Promotion of Science PDF position in Japan (Himeji Institute of Technology, 2001-2003) prior to starting his academic position at McMaster. His research interests in bio-analytical chemistry, separation science, mass spectrometry and metabolomics include the design of novel analytical methods to quantify and identify metabolites of clinical significance in complex biological samples, including new advances in drug screening.  Philip’s laboratory aims to discover new biomarkers that support early detection and treatment of human diseases relevant to population health and preventative medicine with emphasis on inherited metabolic disorders, and chronic human diseases.

 

PEP hours: 1.0

CPS credits: 0

*Note: PEP hours and/or CPS credits will only be awarded upon successful completion of the quiz.

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