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Monoclonal Gammopathies Analysis-Post-gel Era Webinar
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Description: The current available methods to detect M proteins include gel and capillary serum and urine protein electrophoresis (SPEP and UPEP), serum and urine immunofixation (sIFE and uIFE), immunosubstraction (ISUB) and mass spectrometry (MS). Despite an overall good performance on all laboratory procedures using current methodologies, mis-or false-diagnoses have been noticed, especially on cases with non-classic abnormal immunoglobulin profiles. This session will highlight the challenges of transition from traditional agarose gel to Capillary Electrophoresis, as well as cases with the challenging profiles and present solutions using multi-method approach address potential misdiagnosis.
Start Date: Upon registration
Completion: Up to 52 weeks
Credits awarded per Session. See individual Sessions for further details.
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About this item

FREE FOR MEMBERS!

Description: The current available methods to detect M proteins include gel and capillary serum and urine protein electrophoresis (SPEP and UPEP), serum and urine immunofixation (sIFE and uIFE), immunosubstraction (ISUB) and mass spectrometry (MS). Despite an overall good performance on all laboratory procedures using current methodologies, mis-or false-diagnoses have been noticed, especially on cases with non-classic abnormal immunoglobulin profiles. This session will highlight the challenges of transition from traditional agarose gel to Capillary Electrophoresis, as well as cases with the challenging profiles and present solutions using multi-method approach address potential misdiagnosis.

Start Date: Upon registration

Completion: Up to 52 weeks

 

Course/Activity Information

At the end of this webinar you will:

  • Learn the advantages and limitations of various methodologies used for paraproteinemia analysis
  • Learn the importance and the discrepancies of current serum free light chains assays and their utilization in clinical practice
  • Gain knowledge on up-to-date consensus/guidelines for diagnosis of monoclonal gammopathies

 

Speaker: Jieli (Shirley) Li, MD, PhD, DABCC, NRCC

Jieli Shirley Li, MD, PhD, is an Assistant Professor-Clinical at the Department of Pathology, and Co-Director at the Clinical Chemistry & Toxicology Laboratory. Dr. Li earned her MD and PhD from Shanghai Jiao-Tong University School of Medicine. She completed her fellowship training in clinical chemistry at MD Anderson Cancer Center. Her clinical service and academic interests focus on implementing innovate laboratory tests for in vitro diagnosis, prognosis and treatment planning of cancer and endocrine diseases. Dr. Li has published more than 40 scientific articles and served as Ad Hoc reviewer for 10 journals. She also serves in national societies, such as Clinical and Laboratory Standards Institute (CLSI), American Association for Clinical Chemistry (AACC).

 

Recorded: August 18, 2022

 

PEP hours: 1.0

CPS credits: 0

*Note: PEP hours and/or CPS credits will only be awarded upon successful completion of the quiz.

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