9818-16 Hemolytic Anemias
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Course includes study material and exam.

Description: Increase your ability to differentiate these anemias and relate characteristic laboratory findings to disease states such as hereditary spherocytosis, G-6-PD deficiency, sickle cell disease, thalassemia, warm auto immune hemolytic anemia (WAIHA), hemolytic disease of the newborn, and malaria.

Start Date: Upon registration

Completion: Up to 52 weeks

Course/Activity Information

Learning Outcomes:

  • Define "hemolytic anemia"
  • Differentiate: hemolytic disease, compensated hemolytic anemia, decompensated hemolytic anemia
  • Explain the etiologic and the traditional classification of hemolytic anemias and how they overlap.
  • Outline typical lab findings in a hemolytic anemia in:
  1. Blood
  2. Bone marrow
  3. Plasma, urine and feces
  • Differentiate intravascular hemolysis from extravascular hemolysis
  • Explain the significance in hemolytic anemias of:
  1. Polychromasia and an increased RETIC count
  2. Normoblastemia
  3. Spherocytosis
  4. Hyperbilirubinemia
  5. Hemoglobinemia
  6. Hemoglobinuria
  7. Methemalbuminemia
  8. Hemosiderinuria
  • Explain the etiology and list characteristic lab findings for:
  1. Hereditary spherocytosis
  2. Glucose-6-phosphate dehydrogenase deficiency
  3. Pyruvate kinase deficiency
  4. Sickle cell disease - trait and anemia
  5. Beta thalassemia - minor and major
  6. Warm autoimmune hemolytic anemia (A.I.H.A.)
  7. Hemolytic disease of the newborn
  8. Malaria
  • Define and discuss the etiology only of:
  1. Hereditary elliptocytosis
  2. Hereditary stomatocytosis
  3. Hereditary acanthocytosis (abetalipoproteinemia)
  4. Alpha thalassemia - minor and major
  5. Porphyrias
  6. Cold autoimmune hemolytic anemia (A.I.H.A.)
  7. Drug induced immune hemolytic anemia
  8. Paroxysmal nocturnal hemoglobinuria
  9. Paroxysmal cold hemoglobinuria
  10. Microangiopathic hemolytic anemias
  11. Hemolytic anemias due to:

    - Burns, drugs, chemicals and venoms

    Clostridium and Bartonella

    Plasmodium (malaria) and Babesia


Author: Bill McTaggart, BSc, ART


Version Date: August 2016

PEP hours: 15

CPS credits: 0

*Note: PEP hours and/or CPS credits will only be awarded upon successful completion of Final Exam.

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