9873-14 C-Reactive Protein
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About this item

Course includes study material and exam.

Description: Review the theory of acute phase proteins and their role in innate immunity. The C-Reactive Protein (CRP) test has had applications in assisting in the diagnosis of many disease states and these are reviewed. 

Course/Activity Information

Learning Outcomes:

  • Describe the major functions of the innate immune system
  • Tabulate the most important acute phase reactant proteins and their probable function
  • Outline the structure of CRP and its major properties
  • List the clinical situations where there is only minor elevation of CRP in the blood
  • Describe the role of CRP in screening for inflammatory disease and monitoring inflammation
  • Briefly describe the advantages of the CRP compared to the ESR in monitoring inflammation
  • Describe the briefly principle of methods used to measure CRP
  • In detail describe the limitations of the latex agglutination method
  • List in general terms the sensitivity of the various methods available to measure CRP
  • Describe the sensitivity differences between CRP and hsCRP methods
  • Outline the evidence that supports CRP as a marker in acute coronary syndromes
  • List any other clinical states that the CRP test may have clinical utility
  • Describe the role that hsCRP results may have in stratification of cardiovascular disease
  • Discuss the role that hsCRP plays in cardiovascular diseases


Author:  John Chapman, FCSMLS, FIMLS, CLSp(H)

Version Date: March 2014


PEP hours: 12

CPS credits: 0.6

*Note: PEP hours and/or CPS credits will only be awarded upon successful completion of Final Exam. 

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